Tai's group is always looking for students, postdocs and researchers who love technology and enjoy building medical devices. In particular, his lab has developed photoacoustic imaging that allows peering noninvasively into biological tissues. Compared to conventional optical microscopy, his techniques have increased the penetration by nearly two orders of magnitude, breaking through the optical diffusion limit. Combining rich optical contrast and scalable ultrasonic resolution, photoacoustic imaging is the only modality capable of providing multiscale high-resolution structural, functional, metabolic, and molecular imaging of organelles, cells, tissues, and organs as well as small-animal organisms in vivo.
Broad applications include early-cancer detection, surgical guidance, and brain imaging. For example, it can help surgeons effectively remove breast cancer lumps, reducing the need for follow-up surgeries. Thomas G.
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Professor Yang's research area is biophotonics—the imaging and extraction of information from biological targets through the use of light. His research efforts can be categorized into two major groups: chip-scale microscopy imaging and time-reversal based optical imaging. Professor Chandy builds and analyzes systems that sense and respond to changes. He is currently working on systems that sense and respond to: a seismic events, b threat events such as the introduction of nuclear radiation material, c medical events such a fetal distress, and d events in the power grid.
The systems use sensor networks, cloud computing and event-driven architecture. The theory is based on optimization, control, machine learning and game theory. Professor Gradinaru's work has focused on developing and using optogenetics Gradinaru et al. Prot, to dissect the circuitry underlying neurological disorders such as Parkinson's Gradinaru et al.
Her group is now working to understand how perturbations of neuronal network activity can permanently impact the function and even viability of comprising neurons and ultimately change network properties and animal behavior. Of particular interest to the Gradinaru laboratory are chronic experiences, subtle but persistent actions on brain networks that can cause lasting changes in the structure and function of individual cells and circuits.
Research on these topics has been complicated by the heterogeneous nature of the brain. Professor Gradinaru previously helped develop optical modulators of brain activity and the ability to target them to defined pathways as well as the methods necessary to monitor the influence of such manipulations.
The Gradinaru laboratory will continue to develop and disseminate enabling technologies including delivery vectors; Deverman et al, Nat. Joel W. Burdick Richard L. Hayman Professor of Mechanical Engineering and Bioengineering; Jet Propulsion Laboratory Research Scientist Professor Burdick researches robotic locomotion, sensor-based motion planning algorithms, multi-fingered robotic manipulation, applied nonlinear control theory, neural prosthetics, and medical applications of robotics.
Tim Colonius Frank and Ora Lee Marble Professor of Mechanical Engineering Acoustic waves, especially high-intensity ultrasound and shock waves, are used for medical imaging and, increasingly, in manipulation of cells, tissue, and urinary calculi.
Morteza Gharib Hans W. Liepmann Professor of Aeronautics and Bioinspired Engineering; Booth-Kresa Leadership Chair, Center for Autonomous Systems and Technologies; Director, Graduate Aerospace Laboratories; Director, Center for Autonomous Systems and Technologies Professor Gharib's broad range of research interests in medical engineering can be categorized in three areas: bio-inspired design and engineering; cardiovascular research; and microfluidics.
Julia R. Greer Ruben F.
Robert H. Grubbs Victor and Elizabeth Atkins Professor of Chemistry Professor Grubbs pursues research in: organometallic synthesis and mechanisms; organic synthesis and reagents; and polymer synthesis. Related Information.
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